Chloramphenicol concentrations in sera of patients with typhoid fever being treated with oral or intravenous preparation.
نویسندگان
چکیده
Serum chloramphenicol and chloramphenicol succinate concentrations in patients given equivalent doses of chloramphenicol base either intravenously or orally for typhoid fever were measured by high-performance liquid chromatography. The mean serum chloramphenicol concentrations were significantly lower in the 11 patients treated with intravenous chloramphenicol succinate than in the 15 patients treated with oral chloramphenicol capsules.
منابع مشابه
کوندرودیسپلازی متافیزال معرفی دو بیمار مبتلا به نوع Schmid
Typhoid fever is an endemic disease in Iran and other developing countries. This disease has gradually become resistant to the first line of drugs, and because of this resistancy we have studied a new alternative drug (cefixime) on typhoid fever patients and compared it's effectiveness with chloramphenicol. For this purpose, by a randomized clinical trial in Emam Khomeini hospital between 1995-...
متن کاملمقایسه اثر بخشی داروی سفیکسیم با کلرامفنیکل در درمان بیماران تیفوئیدی مراجعه کننده به بیمارستان امام خمینی از تیرماه 1377 لغایت شهریور 1379
Typhoid fever is an endemic disease in Iran and other developing countries. This disease has gradually become resistant to the first line of drugs, and because of this resistancy we have studied a new alternative drug (cefixime) on typhoid fever patients and compared it's effectiveness with chloramphenicol. For this purpose, by a randomized clinical trial in Emam Khomeini hospital between 1995-...
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Concentrations of ampicillin and chloramphenicol were measured in the serum of patients being treated for acute infections by Salmonella typhi or S. paratyphi A. Ampicillin was administered by the oral or intramuscular routes, whereas chloramphenicol was given orally only. Ampicillin concentrations were highest 1 hr after initiation of intramuscular therapy and 2 hr after oral administration. T...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 34 9 شماره
صفحات -
تاریخ انتشار 1990